Hepg2 fgf21
WebIn addition, FGF21 significantly increased the expression of several proteins related to autophagy both in MSG mice and fat-loaded HepG2 cells, such as microtubule … Web18 mrt. 2024 · FGF21 was first identified as a regulator of body weight and an insulin-independent modulator of glucose uptake (2005). Subsequent work revealed that FGF21 …
Hepg2 fgf21
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Web4 apr. 2014 · HepG2 cells were treated with 200 ng/ml FGF21 and then analyzed with western blot using phospho-ERK1/2 antibodies to identify whether or not ERK1/2 can be … Web1 nov. 2024 · HepG2 and H4IIE cells were purchased from ATCC and maintained in 10% FBS (Gibco, Grand Island, NY) in Dulbecco's Modified Eagle's Medium (ATCC, ... (BAT). …
Web22 dec. 2024 · FGF21 is mainly expressed in hepatocytes in response to FFA, glucose and lack of amino acids. FGF21 acts in the CNS and in the adipose tissue to control glucose, … Webβ-OHB stimulated FGF21 expression and secretion in HepG2 cells. (a) β-OHB significantly upregulated FGF21 gene expression after 12 h treatment in HepG2 cells (*P < 0.05 vs …
Web14 aug. 2024 · Figure 2 Hypoxia-induced change in FGF21 expression is not mediated by HIF in HepG2 cells. HepG2 cells were treated with CoCl 2 or exposed to 1% O 2 in the … WebFGF21 is a potent, extracellularly acting metabolic regulator, whose action was discovered through in vitro phenotypic screening and diet manipulation studies in rodents., unlike …
Web1 aug. 2011 · Glucose and xylitol induced FGF21 gene expression in HepG2 and mouse primary hepatocytes. A: Changes in FGF21 gene expression stimulated by the indicated …
Web1 mei 2011 · To further confirm the above in vivo findings, we next tested the direct effects of different types of FFAs on FGF21 mRNA expression in human HepG2 hepatocytes. … ray sinfieldWebNational Center for Biotechnology Information rays in cresskillWeb28 jul. 2024 · We observed that recombinant FGF21 treatment ameliorated hepatic steatosis and insulin resistance through the upregulation of STAMP2 expression. We further … rays indians predictionWebConsistent with this hypothesis, we observed that the addition of acetoacetate, but not -hydroxy- butyrate, to the HepG2 cell medium induces FGF21 expression in a … rays in cozumelWeb28 jul. 2024 · FGF21 is, however, also expressed in several key metabolic tissues (see “Tissue specificity of FGF21 and FGF21 receptor gene expression” ), and certain … rays indiansWeb29 feb. 2016 · Administration of FGF21 in mice inhibits mTORC1 in the liver, whereas FGF21-deficient mice display pronounced insulin-stimulated mTORC1 activation and … simply doughnuts blackburnWeb28 jul. 2024 · We further observed hepatic iron overload (HIO) and reduced iron exporter, ferroportin expression in the liver samples obtained from human NAFLD patients, and … raysin feuerfest