Parachlorophenylananine
Webparachlorophenylalanine n. a substance that blocks the synthesis of serotonin from tryptophan, resulting in depletion of serotonin from brain cells.
Parachlorophenylananine
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WebBoth p-chlorophenylalanine (PCPA) and PCPA methyl ester were found to reliably induce mouse-killing in non-killer rats only when unusually large doses were used (three … Fenclonine, also known as para-chlorophenylalanine (PCPA), acts as a selective and irreversible inhibitor of tryptophan hydroxylase, which is a rate-limiting enzyme in the biosynthesis of serotonin. It has been used experimentally to treat carcinoid syndrome, but the side effects, mostly hypersensitivity reactions and psychiatric disturbances, have prevente…
WebApr 7, 2013 · noun. a compound which inhibits the synthesis of serotonin from tryptophan, generating an elimination of serotonin from brain cells. PARACHLOROPHENYLALANINE: … WebNational Center for Biotechnology Information
WebThe effect of parachlorophenylalanine (PCPA 300 mg/kg i.p.) on several physiological and behavioral parameters was investigated with telemetric methods in the unrestrained rat. … WebParachlorophenylalanine (PCPA, 300 mg/kg/day … The present study was designed to investigate the role of serotonin and other neurotransmitters namely dopamine (DA), …
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