Splet13. dec. 2024 · Uses for trabectedin Trabectedin injection is used to treat certain types of cancer, including liposarcoma or leiomyosarcoma that cannot be treated with surgery or has spread to other parts of the body. It is used in patients who have received treatment with other medicines. SpletTrabectedin injection is used to treat liposarcoma (a cancer that begins in fat cells) or leiomyosarcoma (a cancer that begins in smooth muscle tissue) that has spread to …
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Splet18. mar. 2024 · Trabectedin is an alkylating agent with the chemical name (1'R,6R,6aR,7R,13S,14S,16R)-5- (acetyloxy)-3',4',6,6a,7,13,14,16- octahydro-6',8,14-trihydroxy-7',9-dimethoxy-4,10,23-trimethyl-spiro [6,16- (epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo [7,8]isoquino [3,2-b] [3]benzazocine-20,1' (2'H)-isoquinolin]-19-one. Splet28. apr. 2024 · A randomized phase III trial comparing trabectedin to best supportive care in patients with pre-treated soft tissue sarcoma: T-SAR, a French Sarcoma Group trial A. Le Cesne A. Le Cesne Correspondence Correspondence to:Dr Axel Le Cesne, Medical Oncology Department, Gustave Roussy, 114, rue Edouard Vaillant, 94805 Villejuif, France.
Splet17. okt. 2016 · In addition, trabectedin may cause hepatotoxicity. (See Hepatic Toxicity under Cautions.) The prescribing information indicates that trabectedin should not be used in patients with moderate to severe hepatic impairment and states that there is no recommended dosage of the drug in patients with serum bilirubin concentrations … SpletWhat is this drug used for? It is used to treat soft tissue sarcoma. It may be given to you for other reasons. Talk with the doctor. What do I need to tell my doctor BEFORE I take this drug? If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
Splet15. dec. 2015 · Trabectedin injection is used to treat liposarcoma (a cancer that begins in fat cells) or leiomyosarcoma (a cancer that begins in smooth muscle tissue) that has … SpletIndications and dose For trabectedin Treatment of advanced soft-tissue sarcoma when treatment with anthracyclines and ifosfamide has failed or is contra-indicated, Treatment of relapsed platinum-sensitive ovarian cancer (in combination with pegylated liposomal doxorubicin) for trabectedin By intravenous infusion
Splet11. mar. 2024 · The starting dose-level for T, 1.3 mg/m 2 was chosen based on previous accumulated experience, since this dose had shown activity in the context of myxoid …
SpletTrabectedin This information from Lexicomp explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. Brand Names: US Yondelis Brand Names: Canada Yondelis What is this drug used for? It is used to treat soft tissue sarcoma. mau ghe sofaSplet15. dec. 2015 · vomiting. difficulty concentrating. confusion. chest pain. shortness of breath. swelling of your legs, ankles, or feet. muscle pain or weakness. Trabectedin injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication. heritage lincoln mercury syracuse nySplet22. nov. 2024 · Trabectedin is a natural product derived from the Caribbean sea squirt which has antineoplastic activity and is used to treat soft tissue sarcoma. Trabectedin therapy is associated with a high rate of transient … maughlin dark souls 2Splet22. sep. 2024 · YONDELIS (trabectedin) for injection, for ... Table of Contents Table of Contents 1 INDICATIONS AND USAGE YONDELIS® is indicated for the treatment of … maughns holystoneSplettrabectedin (Rx) Brand and Other Names: Yondelis Classes: Antineoplastics, Alkylating Dosing & Uses AdultPediatric Dosage Forms & Strengths lyophilized powder for … maughold churchSplet• Administer at 1.5 mg/m2body surface area as a 24-hour intravenous infusion, every 3 weeks through a central venous line (2.1, 2.5) • Premedication: dexamethasone 20 mg … maughold church iomSplet07. maj 2024 · Additionally, when using trabectedin in combination with PLD for ROC, cumulative anthracycline dose ≥300 mg/m 2 and prior cardiac medication may increase the risk of cTEAEs if prior lines of therapy involved PLD. maughold buckshaft road cinderford